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건선 치료시 Etretinate와 PUVA의 병용요법에 대한 임상적 고찰

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Author(s)
박의수이규석송준영
Alternative Author(s)
Park, Eui SooLee, Kyu SukSong, Joon Young
Issued Date
1990
Keyword
EtretinatePsoriasisPUVARePUVA
Abstract
RePUVA therapy is the combination of an oral aromatic retinoid(Etretinate) with oral photochemotherapy(PUVA) for the treatment of psoriasis. This combination therapy has the advantage of faster clearance with fewer side effects. Thirty ambulatory psoriasis patients received RePUVA treatment. Etretinate was administered in a dosage of 0.75㎎/㎏ body weight, and PUVA was tried two times per week. Initial response of RePUVA therapy occured in patients with an average of 13.8±9.5 day, 6.0±2.8 irradiation and an accumulated ultraviolet A(UVA) dose of 6.8±4.8J/㎠. Clearance of lesion occured in 53% of patients with an average of 115.1±63.5day, 20.1±6.5 irradiation and an accumulated ultraviolet A(UVA) does of 38.9±17.7J/㎠. Side effects were occured in 27 patients. Dry skin & lip was most prominent side effect and erythematous pruritus, massive desquamation were followed. GI trouble, brittle nail, hair loss manifested, too.
Alternative Title
Clinical Evaluation
of Etretinate and PUVA Combination Therapy in Psoriasis
Department
Dept. of Dermatology (피부과학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.9(4) : 445-449, 1990
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14658
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1990
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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