건선 치료시 Etretinate와 PUVA의 병용요법에 대한 임상적 고찰

Other Titles
Clinical Evaluation of Etretinate and PUVA Combination Therapy in Psoriasis
Authors
노용지최윤애박의수이규석송준영
Department
Dept. of Dermatology (피부과학)
Issue Date
1990
Citation
Keimyung Medical Journal, Vol.9(4) : 445-449, 1990
Abstract
RePUVA therapy is the combination of an oral aromatic retinoid(Etretinate) with oral photochemotherapy(PUVA) for the treatment of psoriasis. This combination therapy has the advantage of faster clearance with fewer side effects. Thirty ambulatory psoriasis patients received RePUVA treatment. Etretinate was administered in a dosage of 0.75㎎/㎏ body weight, and PUVA was tried two times per week. Initial response of RePUVA therapy occured in patients with an average of 13.8±9.5 day, 6.0±2.8 irradiation and an accumulated ultraviolet A(UVA) dose of 6.8±4.8J/㎠. Clearance of lesion occured in 53% of patients with an average of 115.1±63.5day, 20.1±6.5 irradiation and an accumulated ultraviolet A(UVA) does of 38.9±17.7J/㎠. Side effects were occured in 27 patients. Dry skin & lip was most prominent side effect and erythematous pruritus, massive desquamation were followed. GI trouble, brittle nail, hair loss manifested, too.
Keywords
EtretinatePsoriasisPUVARePUVA
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14658
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
2. Keimyung Medical Journal (계명의대 학술지) > 1990
Keimyung Author(s)
박의수; 이규석; 송준영
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