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당뇨병환자에 있어서 치료방법 선정에 식후 2시간 혈청 C-peptide치와 Glucagon자극후 혈청 C-peptide치의 의의

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Affiliated Author(s)
이인규안성훈
Alternative Author(s)
Lee, In KyuAhn, Sung Hoon
Journal Title
Keimyung Medical Journal
Issued Date
1990
Keyword
C-peptideDiabetesGlucagon
Abstract
Basal, postprandial (2hour after breakfast), and glucagon stimulated serum C-peptide concentrations were determined in 22 patients with diabetes who admitted in Keimyung University Dongsan Medical Center and Youngnam University Hospital. Basal and postprandial C-peptide values were measured on two consecutive days to estimate the degree of variation of C-peptide secretion. The results were as follows: 1. Mean fasting and postprandial C-peptide concentrations in 15 insulin requiring diabetic patients were 0.7±0.2ng/ml, 1.1±0.3ng/ml on first day. 0.9±0.4ng/ml, 1.1±0.4ng/ml on second day and in non insulin requiring diabetic patients were 1.5±0.5ng/ml, 2.5±0.7ng/ml on first day. 1.5±0.5ng/ml, 2.8±0.7ng/ml on second day. The mean C-peptide values of 15 insulin requiring diabetic patients were significantly lower than those of 7 non insulin requiring diabetic patients(p<0.05, p<0.001). 2. There were no differences in fasting and postprandial C-peptide values between two consecutive day. 3. The postprandial C-peptide valued on two consecutive days were postiviely correlated with the serum C-peptide values after a glucagon administration(r=0.86, 0.75). Above results suggested that postprandial and glucagon stimulated C-peptide valued are very sensitive guides for a insulin treatment in patients with diabetes.
Alternative Title
Glucagon-Stimulated
and Postprandial Plasma C-peptide Values as a Guide for Insulin Treatment in Patients with Diabetes
Department
Dept. of Internal Medicine (내과학)
Publisher
Keimyung University School of Medicine
Citation
서영숙 et al. (1990). 당뇨병환자에 있어서 치료방법 선정에 식후 2시간 혈청 C-peptide치와 Glucagon자극후 혈청 C-peptide치의 의의. Keimyung Medical Journal, 9(4), 455–460.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14660
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1990
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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