반코마이신 정주투여후 발생한 위막성 대장염 1례

Other Titles
Pseudomembranous Colitis Secondary to Intravenous Vancomycin
Authors
박진용이동욱권순대한승묵황준영이인규박근용류성열김미정신동우김성종여준기
Department
Dept. of Internal Medicine (내과학); Institute for Medical Science (의과학 연구소)
Issue Date
1998
Citation
Keimyung Medical Journal, Vol.17(3) : 421-428, 1998
Abstract
Diarrhea is a common complication of antibiotics usage. The diarrhea ascribed to antibiotics usually consist of loose or watery stools, sometimes containing mucus but rarely gross evident blood. Almost every antibiotics has been implicated. Although the pathogenesis of antibiotics-associated diarrhea is not confirmed, recent studies have shown that a toxin of Clostridium difficile is implicated as a cause of it. Diagnosis is made by detecting toxin in the stool or by positive stool culture for C. difficile. Treatment is either directed at binding the toxin with anion exchange resins such as cholestyramine in mile case, or at eradicating the C. difficile organism with oral vancomycin, metronidazole for more severe cases. We have recently experienced one patient who developed diarrhea, abdomminal pain after having received prolonged vancomycin injection. Sigmoidoscopic finding revealed typical cream-colored plaque lesions (pseudomembrane) on a red friable edematous mucosa. Light microscopic finding of the rectal mucosa showed a volcano-like appearance. The symptom improved after treatment with oral vancomycin and metronidazole. So, we report one case of pseudomembranous colitis secondary to the use of parenteral vancomycin.
Keywords
Pseudomembranous colitisIntravenous vancomycin
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15102
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. Journal Papers (연구논문) > 3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
2. Keimyung Medical Journal (계명의대 학술지) > 1998
Keimyung Author(s)
류성열; 박근용; 이인규
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