마르졸랭 궤양의 치료와 임상적 고찰

Other Titles
Clinical Study of Marjolin's Ulcer
Authors
최동원
Department
Dept. of Plastic Surgery (성형외과학); Institute for Medical Science (의과학 연구소)
Issue Date
1999
Citation
Keimyung Medical Journal, Vol.18(1) : 101-108, 1999
Abstract
Marjolin's ulcers are malignancies that arise at sites of chronic burn scar wound as well as chronic inflammatory focus such as osteomyelitis, venous stasis, frostbite and urinary fistula, etc. The precise pathogenesis of burn scar carcinoma is not entirely known. However the features that may predispose to malignant transformation of the ulcer include a prolonged healing phase and repetitive trauma. As the rate of malignant transformation is low, there has been no established knowledge regarding clinical characteristics, treatment modality and long-term prognosis. The author experienced and evaluated 10 patients diagnosed as Marjolin's ulcer during 6 years since 1991 and all was ascertained to be squamous cell carcinoma upon histological examiniation. The causative injuries were mostly burn except one case of cart wheel injury and the locations of the lesions were limited to lower extremity except one case of chest. The mean latent period was 36 years and the mean age when diagnosed was 54 years. Seven of 10 patients received wide excisions and skin grafts and 2 received local flap coverages and 1 refused surgery. Two major morbidities were encountered, one underwent above-knee amputation due to recurrence at 8 months postoperatively and the other died of distant metastasis. All clinicians of every specialty are advised to pay attention in the long-term surveillance of all significant scars or areas of chronic inflammation.
Keywords
Marjolin's ulcerBurn scar carcinomaSquamous cell carcinoma
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15127
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Plastic Surgery (성형외과학)
1. Journal Papers (연구논문) > 3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
2. Keimyung Medical Journal (계명의대 학술지) > 1999
Keimyung Author(s)
최동원
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