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유방암환자에서 감시 림프절 생검의 임상적 경험

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Affiliated Author(s)
강선희정기용김유사전석길권선영
Alternative Author(s)
Kang, Sun HeeChung, Ki YongKim, You SahZeon, Seok KilKwon, Sun Young
Journal Title
Keimyung Medical Journal
Issued Date
2005
Keyword
Axillary dissectionBreast cancerSentinel lymph node
Abstract
Axillary nodal status is the single most important predictor of disease outcome in patients with breast cancer and also the best guide for adjuvant therapy. Sentinel lymph node biopsy (SLN) is an established, minimally invasive means of staging the axilla in patients with breast cancer. We did a retrospective analysis to evaluate the success rate, sensitivity, false negative rate of SLN localization in early breast caner. A retrospective annalysis was performed of 223 breast cancer patients who underwent SLN biopsy with radiopharmaceutical and blue dye for SLN identification from December 1998 to June 2005. All SLNs were submitted for intraoperative frozen section analysis, touch preparation, and hematoxylin and eosin stain. The mean age at diagnosis was 48.56 years, the mean tumor size was 1.98cm, and the mean number of SLNs was 1.4. The detection rate of SLN through whole period with both agent was 97.2%, the sensitivity 96.2% and false negative rate 3.8%. The detection rate and the false negative rate had improved after thd learning period. The false negative rate for tumors less the 2 cm was significantly lower than that for tumors greater than 2 cm. The addition of a radiopharmaceutical and the dye in SLN biopsy inceases the detection rate of SLNs in breast cancer patients after learning period and SLN biospy may be applicable to breast cancer patients and thereby allow the omission of routine axillary dissection in selected cases.
Alternative Title
Clinical Experience of Sentinel Lymph Node Biopsy in Breast Cancer
Department
Dept. of Surgery (외과학)
Dept. of Nuclear Medicine (핵의학)
Dept. of Pathology (병리학)
Publisher
Keimyung University School of Medicine
Citation
김미선 et al. (2005). 유방암환자에서 감시 림프절 생검의 임상적 경험. Keimyung Medical Journal, 24(2), 105–111.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15346
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2005
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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