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일과성 심근 허혈에 민감한 조기 표지자로서 Ischemic Modified Albumin의 역활

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Author(s)
김권배김형섭남창욱한성욱허승호김윤년
Alternative Author(s)
Kim, Kwon BaeKim, Hyung SeopNam, Chang WookHan, Seong WookHur, Seung HoKim, Yoon Nyun
Issued Date
2006
Keyword
AlbuminMyocardial ischemiaPercutaneous transluminal coronary angioplasty
Abstract
Human albumin undergoes a significant reduction in its capacity to bind exogenous cobalt soon after transient coronary occlusion by percutaneous transluminal coronary angioplasty (PTCA). We investigated the changes of ischemic modified albumin(IMA) level following transient myocardial ischemia. We enrolled forty patients who diagnosed as chronic stable angina. These patients divided into 2 groups. Twenty seven patients who underwent PTCA were as group 1, 13 patients who underwent diagnostic coronary angiography as group 2. Venous samples were
obtained 15 minutes, 1 hour, 6 hours and 12 hours after procedures. In group 1, the level of IMA
was 97.7±15.4 U/mL at basal and 116.6±13.1 U/mL at 15 minutes, which was significantly increased than basal. In group 2, The IMA level was significantly increased from basal (96.0±6.8 U/mL) to 15 minutes (104.3±6.6 U/mL). The difference IMA levels was statistically significant (p<0.001) in both groups until 1 hour. The changes of the IMA can be an early sensitive marker of transient myocardial ischemia and may have a role in very early ischemic event.
Alternative Title
Role of Ischemic Modified Albumin as Early Sensitive Marker of Transient Myocardial Ischemia
Department
Dept. of Internal Medicine (내과학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.25(2) : 167-173, 2006
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15379
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2006
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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