일과성 심근 허혈에 민감한 조기 표지자로서 Ischemic Modified Albumin의 역활

Other Titles
Role of Ischemic Modified Albumin as Early Sensitive Marker of Transient Myocardial Ischemia
Authors
김민정김권배전동환조현옥박창욱김형섭남창욱한성욱허승호김윤년이영수김기식
Department
Dept. of Internal Medicine (내과학)
Citation
Keimyung Medical Journal, Vol.25(2) : 167-173, 2006
Abstract
Human albumin undergoes a significant reduction in its capacity to bind exogenous cobalt soon after transient coronary occlusion by percutaneous transluminal coronary angioplasty (PTCA). We investigated the changes of ischemic modified albumin(IMA) level following transient myocardial ischemia. We enrolled forty patients who diagnosed as chronic stable angina. These patients divided into 2 groups. Twenty seven patients who underwent PTCA were as group 1, 13 patients who underwent diagnostic coronary angiography as group 2. Venous samples were obtained 15 minutes, 1 hour, 6 hours and 12 hours after procedures. In group 1, the level of IMA was 97.7±15.4 U/mL at basal and 116.6±13.1 U/mL at 15 minutes, which was significantly increased than basal. In group 2, The IMA level was significantly increased from basal (96.0±6.8 U/mL) to 15 minutes (104.3±6.6 U/mL). The difference IMA levels was statistically significant (p<0.001) in both groups until 1 hour. The changes of the IMA can be an early sensitive marker of transient myocardial ischemia and may have a role in very early ischemic event.
Keywords
AlbuminMyocardial ischemiaPercutaneous transluminal coronary angioplasty
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15379
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2006
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
김권배; 김형섭; 남창욱; 한성욱; 허승호; 김윤년
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