Assessment of Diabetic Peripheral Neuropathy Using Current Perception Threshold

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Assessment of Diabetic Peripheral Neuropathy Using Current Perception Threshold
Kyoung Tae KimSoyoung Lee
Dept. of Rehabilitation Medicine (재활의학)
Issue Date
Keimyung Medical Journal, Vol.36(1) : 18-25, 2017
The aim of this study was to compare the current perception threshold (CPT) with a nerve conduction study (NCS) to evaluate the usefulness of CPT in the diagnosis of diabetic Peripheral Neuropathy (DPN). CPT measurement is quantitative method for assessment of peripheral sensory nerve function using electrical impulse. Enrolled in this study were 142 patients with type 2 diabetes who underwent both CPT testing and NCS between January 2013 and April 2016. DPN was diagnosed by NCS. CPT was performed on the right index finger and great toe of each patient. Patients with burning, tingling sensation and with longer history of diabetes tended to have a higher prevalence of DPN. In all frequencies tested (2000, 250, 5 Hz), CPT values of the DPN group were higher than the normal group. After classification in either the normoesthesia or hypoesthesia group according to CPT, the DPN group had a significantly higher prevalence of hypoesthesia than normal group. The receiver operating characteristics curve analysis showed that CPT had a high area under curve value for predicting the presence of DPN. In conclusion, CPT measurement is clinically valuable in detecting nerve dysfunction in patients with type 2 diabetes.
Current perception thresholdDiabetic neuropathyNerve conduction study
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학)
2. Keimyung Medical Journal (계명의대 학술지) > 2017
Keimyung Author(s)
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