Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding

Authors
Yoo Jin LeeBo Ram MinEun Soo KimKyung Sik ParkKwang Bum ChoByoung Kuk JangWoo Jin ChungJae Seok HwangSeong Woo Jeon
Department
Dept. of Internal Medicine (내과학)
Issue Date
2016
Citation
Korean Journal of Internal Medicine, Vol.31(1) : 54-64, 2016
ISSN
1226-3303
Abstract
Background/Aims: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition. Methods: A prospective observational study was conducted at a single hospital between April 2010 and November 2012, and 336 patients with symptoms and signs of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics and endoscopic findings were reviewed to identify potential factors associated with 30-day mortality. Results: Overall, 184 patients were included in the study (men, 79.3%; mean age, 59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age ≥ 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization were significant predictive factors of 30-day mortality. Conclusions: Comorbidity of DM or metastatic malignancy, age ≥ 65 years, and hemodynamic instability during hospitalization were predictors of 30-day mortality in patients with NVUGIB. These results will help guide the management of patients with this condition.
Keywords
Gastrointestinal hemorrhageMortalityPrognosisComorbidity
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/33260
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
이유진; 김은수; 박경식; 조광범; 장병국; 정우진; 황재석
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