Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding
- Affiliated Author(s)
- 이유진; 김은수; 박경식; 조광범; 장병국; 정우진; 황재석
- Alternative Author(s)
- Lee, Yoo Jin; Kim, Eun Soo; Park, Kyung Sik; Cho, Kwang Bum; Jang, Byoung Kuk; Chung, Woo Jin; Hwang, Jae Seok
- Journal Title
- Korean Journal of Internal Medicine
- ISSN
- 1226-3303
- Issued Date
- 2016
- Keyword
- Gastrointestinal hemorrhage; Mortality; Prognosis; Comorbidity
- Abstract
- Background/Aims: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a
common medical emergency that can be life threatening. This study evaluated
predictive factors of 30-day mortality in patients with this condition.
Methods: A prospective observational study was conducted at a single hospital between
April 2010 and November 2012, and 336 patients with symptoms and signs
of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics
and endoscopic findings were reviewed to identify potential factors associated
with 30-day mortality.
Results: Overall, 184 patients were included in the study (men, 79.3%; mean age,
59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed
that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age
≥ 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization
were significant predictive factors of 30-day mortality.
Conclusions: Comorbidity of DM or metastatic malignancy, age ≥ 65 years, and
hemodynamic instability during hospitalization were predictors of 30-day mortality
in patients with NVUGIB. These results will help guide the management of
patients with this condition.
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