한국 성인에서 렘수면의존폐쇄수면무호흡증 환자의 임상양상

Other Titles
Clinical Characteristics of REM-Dependent Obstructive Sleep Apnea in Korean Adults
Authors
문혜진임상훈김도형김동은황상희조용원
Department
Dept. of Neurology (신경과학); Dept. of Otorhinolaryngology (이비인후과학); Dept. of Dentistry (치과학)
Issue Date
2016
Citation
대한신경과학회, Vol.34(2) : 124-129, 2016
ISSN
1225-7044
Abstract
Background: Rapid-eye-movement-sleep-dependent obstructive sleep apnea (REM-OSA) is a sleep breathing abnormality in which apneas/hypopneas occur mainly during REM sleep periods. However, the clinical significance of REM-OSA compared to sleep-stage-non-dependent OSA (SND-OSA) has been controversial. This study evaluated differences in the clinical features, polysomnography (PSG) characteristics, and subjective symptoms between REM-OSA and SND-OSA. Methods: In total, 136 consecutive patients with mild-to-moderate OSA were enrolled. REM-OSA was defined as a rapid eye movement (REM):non-REM apnea-hypopnea index (AHI) ratio of >2 and a total duration of REM sleep exceeding 30 minutes. We compared the demographic, clinical, and PSG characteristics, and subject symptoms between REM-OSA and SND-OSA. Results: The REM-OSA group comprised 45 (33%) of the 136 subjects. The mean age and total AHI did not differ between the groups, but there was a significant female predominance (35.6% vs. 16.5%) in the REM-OSA group. In terms of PSG parameters, subjects with REM-OSA showed a lower percentage of light sleep and a lower AHI in a supine position despite spending more sleep time in that position. Subjective sleep complaints, depression, anxiety, and health-related quality of life did not differ between the two study groups. Conclusions: The female predominance and sleep architecture differed between REM-OSA and SND-OSA in this study. The AHI in subjects with SND-OSA was dependent on sleep position rather than sleep stage. Further study is needed to elucidate the pathomechanism and clinical significance of REM-OSA.
Keywords
REM-dependent OSAREM-related OSAREM-dependent sleep apneaREM sleepObstructive sleep apneaPolysomnography
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/33366
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학)
Keimyung Author(s)
문혜진; 조용원; 김동은; 황상희
File in this Item
oak-2016-0326.pdf(427.14 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE