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한국 성인에서 렘수면의존폐쇄수면무호흡증 환자의 임상양상

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Author(s)
문혜진임상훈김도형김동은황상희조용원
Keimyung Author(s)
Moon, Hye JinCho, Yong WonKim, Dong EunHwang, Sang Hee
Department
Dept. of Neurology (신경과학)
Dept. of Otorhinolaryngology (이비인후과학)
Dept. of Dentistry (치과학)
Journal Title
대한신경과학회
Issued Date
2016
Volume
34
Issue
2
Keyword
REM-dependent OSAREM-related OSAREM-dependent sleep apneaREM sleepObstructive sleep apneaPolysomnography
Abstract
Background: Rapid-eye-movement-sleep-dependent obstructive sleep apnea (REM-OSA) is a sleep breathing abnormality
in which apneas/hypopneas occur mainly during REM sleep periods. However, the clinical significance of REM-OSA
compared to sleep-stage-non-dependent OSA (SND-OSA) has been controversial. This study evaluated differences in the
clinical features, polysomnography (PSG) characteristics, and subjective symptoms between REM-OSA and SND-OSA.
Methods: In total, 136 consecutive patients with mild-to-moderate OSA were enrolled. REM-OSA was defined as a rapid eye
movement (REM):non-REM apnea-hypopnea index (AHI) ratio of >2 and a total duration of REM sleep exceeding 30
minutes. We compared the demographic, clinical, and PSG characteristics, and subject symptoms between REM-OSA and
SND-OSA.
Results: The REM-OSA group comprised 45 (33%) of the 136 subjects. The mean age and total AHI did not differ between
the groups, but there was a significant female predominance (35.6% vs. 16.5%) in the REM-OSA group. In terms of PSG
parameters, subjects with REM-OSA showed a lower percentage of light sleep and a lower AHI in a supine position despite
spending more sleep time in that position. Subjective sleep complaints, depression, anxiety, and health-related quality of life
did not differ between the two study groups.
Conclusions: The female predominance and sleep architecture differed between REM-OSA and SND-OSA in this study. The
AHI in subjects with SND-OSA was dependent on sleep position rather than sleep stage. Further study is needed to elucidate
the pathomechanism and clinical significance of REM-OSA.
Alternative Title
Clinical Characteristics of REM-Dependent Obstructive Sleep Apnea
in Korean Adults
Keimyung Author(s)(Kor)
문혜진
조용원
김동은
황상희
Publisher
School of Medicine
Citation
문혜진 et al. (2016). 한국 성인에서 렘수면의존폐쇄수면무호흡증 환자의 임상양상. 대한신경과학회, 34(2), 124–129. doi: 10.17340/jkna.2016.2.6
Type
Article
ISSN
1225-7044
DOI
10.17340/jkna.2016.2.6
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33366
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학)
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