Successful Treatment of Disseminated Adenovirus Infection With Ribavirin and Intravenous Immunoglobulin in an Adult Renal Transplant Recipient: A Case Report

Authors
U.J. ParkS.K. HyunH.T. KimW.H. ChoS.Y. Han
Department
Dept. of Surgery (외과학); Dept. of Internal Medicine (내과학)
Issue Date
2015
Citation
Transplantation Proceedings, Vol.47(3) : 791-793, 2015
ISSN
0041-1345
Abstract
Disseminated adenovirus infection in recipients of renal transplants is a rare but often fatal complication. We present a case of a 32-year-old woman who underwent renal trans- plantation from a deceased donor. Ten months after transplantation, she presented with dysuria, hematuria, and febrile illness. Despite the use of antibiotics, the patient’s symp- toms continued and worsened and the serum creatinine level was increased. The results of urine and serum polymerase chain reaction were positive for adenovirus. Renal biopsy revealed viral interstitial nephritis. The patient was treated with ribavirin, intravenous immunoglobulin, and reduction in immunosuppression. Her symptoms progressively improved from 7 days after the treatment. Serum and urine polymerase chain reaction for adenovirus became negative 10 and 21 days after the treatment, respectively. She remained in good health with excellent allograft function 6 months later.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/34701
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
Keimyung Author(s)
박의준; 김형태; 조원현; 한승엽
Full Text
https://www.sciencedirect.com/science/article/pii/S0041134515001438?via%3Dihub
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