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Successful Treatment of Disseminated Adenovirus Infection With Ribavirin and Intravenous Immunoglobulin in an Adult Renal Transplant Recipient: A Case Report

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Author(s)
U.J. ParkS.K. HyunH.T. KimW.H. ChoS.Y. Han
Keimyung Author(s)
Park, Ui JunKim, Hyoung TaeCho, Won HyunHan, Seung Yeup
Department
Dept. of Surgery (외과학)
Dept. of Internal Medicine (내과학)
Journal Title
Transplantation Proceedings
Issued Date
2015
Volume
47
Issue
3
Abstract
Disseminated adenovirus infection in recipients of renal transplants is a rare but often fatal
complication. We present a case of a 32-year-old woman who underwent renal trans-
plantation from a deceased donor. Ten months after transplantation, she presented with
dysuria, hematuria, and febrile illness. Despite the use of antibiotics, the patient’s symp-
toms continued and worsened and the serum creatinine level was increased. The results of
urine and serum polymerase chain reaction were positive for adenovirus. Renal biopsy
revealed viral interstitial nephritis. The patient was treated with ribavirin, intravenous
immunoglobulin, and reduction in immunosuppression. Her symptoms progressively
improved from 7 days after the treatment. Serum and urine polymerase chain reaction for
adenovirus became negative 10 and 21 days after the treatment, respectively. She remained
in good health with excellent allograft function 6 months later.
Keimyung Author(s)(Kor)
박의준
김형태
조원현
한승엽
Publisher
School of Medicine
Citation
U.J. Park et al. (2015). Successful Treatment of Disseminated Adenovirus Infection With Ribavirin and
Intravenous Immunoglobulin in an Adult Renal Transplant Recipient: A Case Report. Transplantation Proceedings, 47(3), 791–793. doi: 10.1016/j.transproceed.2014.11.054
Type
Article
ISSN
0041-1345
Source
https://www.sciencedirect.com/science/article/pii/S0041134515001438?via%3Dihub
DOI
10.1016/j.transproceed.2014.11.054
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34701
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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