결핵성 파괴폐의 흉부 전산화단층촬영 소견 및 폐기능과의 상관관계

Other Titles
CT Radiologic Findings in Patients with Tuberculous Destroyed Lung and Correlation with Lung Function
Authors
채진녕정치영심상우노병학전영준
Department
Dept. of Internal Medicine (내과학); Dept. of Radiology (영상의학)
Issue Date
2011
Citation
Tuberculosis and Respiratory Diseases, Vol.71(3) : 202-209, 2011
ISSN
1738-3536
Abstract
Background A tuberculous destroyed lung is sequelae of pulmonary tuberculosis and causes various respiratory symptoms and pulmonary dysfunction. The patients with a tuberculous destroyed lung account for a significant portion of those with chronic lung disease in Korea. However, few reports can be found in the literature. We investigated the computed tomography (CT) findings in a tuberculous destroyed lung and the correlation with lung function. Methods A retrospective analysis was carried out for 44 patients who were diagnosed with a tuberculous destroyed lung at the Keimyung University Dongsan Hospital between January 2004 and December 2009. Results A chest CT scan showed various thoracic sequelae of tuberculosis. In lung parenchymal lesions, there were cicatrization atelectasis in 37 cases (84.1%) and emphysema in 13 cases. Bronchiectasis (n=39, 88.6%) was most commonly found in airway lesions. The mean number of destroyed bronchopulmonary segments was 7.7 (range, 4~14). The most common injured segment was the apicoposterior segment of the left upper lobe (n=36, 81.8%). In the pulmonary function test, obstructive ventilatory defects were observed in 31 cases (70.5%), followed by a mixed (n=7) and restrictive ventilatory defect (n=5). The number of destroyed bronchopulmonary segments showed a significant negative correlation with forced vital capacity (FVC), % predicted (r=-0.379, p=0.001) and forced expiratory volume in one second (FEV1), % predicted (r=-0.349, p=0.020). After adjustment for age and smoking status (pack-years), the number of destroyed segments also showed a significant negative correlation with FVC, % predicted (B=-0.070, p=0.014) and FEV1, % predicted (B=-0.050, p=0.022). Conclusion Tuberculous destroyed lungs commonly showed obstructive ventilatory defects, possibly due to bronchiectasis and emphysema. There was negative correlation between the extent of destruction and lung function. Keywords: Tuberculosis, Pulmonary/complications; Lung Diseases, Obstructive; Tuberculosis; Bronchiectasis
Keywords
TuberculosisPulmonary/complicationsLung DiseasesObstructiveBronchiectasis
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/34782
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
Keimyung Author(s)
정치영; 전영준; 노병학
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