계명대학교 의학도서관 Repository

Innate immunity markers in culprit plaques of acute myocardial infarction or stable angina

Metadata Downloads
Author(s)
황일선
Alternative Author(s)
Hwang, Il Seon
Publication Year
2012
Abstract
We analyzed the innate immunity markers, C-reactive protein (CRP), serum amyloid P component (SAP) and pentraxin-3 (PTX-3), and metalloproteinase-9 (MMP-9) in coronary atherectomy tissues obtained from patients with acute ST elevation myocardial infarction (STEMI) (n = 27) or stable angina (n = 15). The relative areas immunopositive for CRP and SAP were similar in the two groups. In contrast, the proportion of areas immunopositive for PTX-3 and MMP-9 was higher in the STEMI group, compared to the stable angina group. PTX-3 or MMP-9-stained areas largely overlapped with those positive for CD68. We concluded that PTX-3 plays a role in the pathogenesis of STEMI.
Keywords: Coronary disease, pentraxins, plaque instability
Department
Dept. of Pathology (병리학)
Publisher
School of Medicine
Citation
Biomarkers, Vol.17(3) : 209-215, 2012
Type
Article
ISSN
1354-750X
DOI
10.3109/1354750X.2011.651158
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35212
Authorize & License
  • AuthorizeOpen
  • EmbargoForever
Files in This Item:

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.