Isolation and Synthesis of Tryptamine Derivatives from a Symbiotic Bacterium Xenorhabdus nematophilus PC
- Affiliated Author(s)
- 서성일; 백승국
- Alternative Author(s)
- Suh, Seong Il; Baik, Seung Kug
- Journal Title
- Bulletin of the Korean Chemical Society
- ISSN
- 0253-2964
- Issued Date
- 2003
- Abstract
- Nematophin and its analog incorporating tryptamine unit have been isolated and characterized from strain XRPC of a symbiotic bacterium Xenorhabdus nematophilus, which was newly isolated from Korean entomopathogenic nematodes. The stereoselective synthesis of these compounds was accomplished, and the relative configurations were determined. Nematophin exhibited potent antibacterial activities over several strains of methicillin-resistant S. aureus (MRSA) comparable to those of vancomycin.
Key Words : Xenorhabdus nematophilus, Staphylococcus aureus, Nematophin, Tryptamine, L-Isoleucine
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.