Two-Year Outcomes of the Sirolimus-Eluting Stent According to Unprotected Left Main Lesion

Authors
Ung KimJong-Seon ParkSang-Hoon SeolTae-Hyun YangSung-Man KimDae-Kyung KimDoo-Il KimDong-Soo KimWon-Jae LeeSang-Hee LeeGeu-Ru HongDong-Gu ShinYoung-Jo KimBong-Sup ShimYoon-Kyung ChoHyung-Seop KimChang-Wook NamSeung-Ho HurKwon-Bae KimYoon-Nyun Kim
Department
Dept. of Internal Medicine (내과학)
Issue Date
2009
Citation
Clinical Cardiology, Vol.32(6) : 332-336, 2009
ISSN
0160-9289
Abstract
Background: The data of long-term outcomes of sirolimus-eluting stent (SES) according to lesion location of unprotected left main coronary artery (LMCA) is scarce. Hypothesis: The purpose of this study was to evaluate the long-term outcomes after implantation of the SES in LMCA. Methods: A total of 84 patients (51 males) who had undergone SES implantation for the treatment of native LMCA stenosis were enrolled. The patients were divided into 2 groups based on angiographic lesion location: those with significant stenosis in the ostium and/or body (group 1; n = 39) and those involving bifurcation (group 2; n = 45). Results: All of the group 1 patients were treated with simple lesion coverage while different stenting techniques were used in group 2 (cross-over: 44.8%, T: 6.7%, kissing: 37.8%, and crush techniques: 11.1%). The 8-month quantitative angiographic findings and in-hospital and 2 year rates of major adverse cardiac events (MACE) were compared between the 2 groups. Although angiographic success and in-hospital MACE rates were similar in both groups with 1 cardiac death due to acute stent thrombosis in group 2, at 2-year follow-up, the MACE rate was significantly higher in group 2 than in group 1 at 2 years (22.2% vs 2.6%, respectively, P = 0.008). Coronary angiography revealed a significantly higher binary restenosis rate in group 2 compared with group 1 (20% vs 0%, respectively, P = 0.003). Conclusions: Interventional treatment using SES in left main lesions showed favorable short-term and long- term outcomes in selected patients with lesion location being an important determinant of clinical and angiographic outcomes.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35487
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
조윤경; 김형섭; 남창욱; 허승호; 김권배; 김윤년
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/clc.20563/epdf
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