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Two-Year Outcomes of the Sirolimus-Eluting Stent According to Unprotected Left Main Lesion

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Author(s)
Ung KimJong-Seon ParkSang-Hoon SeolTae-Hyun YangSung-Man KimDae-Kyung KimDoo-Il KimDong-Soo KimWon-Jae LeeSang-Hee LeeGeu-Ru HongDong-Gu ShinYoung-Jo KimBong-Sup ShimYoon-Kyung ChoHyung-Seop KimChang-Wook NamSeung-Ho HurKwon-Bae KimYoon-Nyun Kim
Publication Year
2009
Abstract
Background: The data of long-term outcomes of sirolimus-eluting stent (SES) according to lesion location of
unprotected left main coronary artery (LMCA) is scarce.
Hypothesis: The purpose of this study was to evaluate the long-term outcomes after implantation of the SES
in LMCA.
Methods: A total of 84 patients (51 males) who had undergone SES implantation for the treatment of native
LMCA stenosis were enrolled. The patients were divided into 2 groups based on angiographic lesion location:
those with significant stenosis in the ostium and/or body (group 1; n = 39) and those involving bifurcation
(group 2; n = 45).
Results: All of the group 1 patients were treated with simple lesion coverage while different stenting techniques
were used in group 2 (cross-over: 44.8%, T: 6.7%, kissing: 37.8%, and crush techniques: 11.1%). The 8-month
quantitative angiographic findings and in-hospital and 2 year rates of major adverse cardiac events (MACE)
were compared between the 2 groups. Although angiographic success and in-hospital MACE rates were similar
in both groups with 1 cardiac death due to acute stent thrombosis in group 2, at 2-year follow-up, the MACE
rate was significantly higher in group 2 than in group 1 at 2 years (22.2% vs 2.6%, respectively, P = 0.008).
Coronary angiography revealed a significantly higher binary restenosis rate in group 2 compared with group 1
(20% vs 0%, respectively, P = 0.003).
Conclusions: Interventional treatment using SES in left main lesions showed favorable short-term and long-
term outcomes in selected patients with lesion location being an important determinant of clinical and
angiographic outcomes.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Clinical Cardiology, Vol.32(6) : 332-336, 2009
Type
Article
ISSN
0160-9289
DOI
10.1002/clc.20563
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35487
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