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Two-Year Outcomes of the Sirolimus-Eluting Stent According to Unprotected Left Main Lesion

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Author(s)
Ung KimJong-Seon ParkSang-Hoon SeolTae-Hyun YangSung-Man KimDae-Kyung KimDoo-Il KimDong-Soo KimWon-Jae LeeSang-Hee LeeGeu-Ru HongDong-Gu ShinYoung-Jo KimBong-Sup ShimYoon-Kyung ChoHyung-Seop KimChang-Wook NamSeung-Ho HurKwon-Bae KimYoon-Nyun Kim
Keimyung Author(s)
Cho, Yun KyeongKim, Hyung SeopNam, Chang WookHur, Seung HoKim, Kwon BaeKim, Yoon Nyun
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical Cardiology
Issued Date
2009
Volume
32
Issue
6
Abstract
Background: The data of long-term outcomes of sirolimus-eluting stent (SES) according to lesion location of
unprotected left main coronary artery (LMCA) is scarce.
Hypothesis: The purpose of this study was to evaluate the long-term outcomes after implantation of the SES
in LMCA.
Methods: A total of 84 patients (51 males) who had undergone SES implantation for the treatment of native
LMCA stenosis were enrolled. The patients were divided into 2 groups based on angiographic lesion location:
those with significant stenosis in the ostium and/or body (group 1; n = 39) and those involving bifurcation
(group 2; n = 45).
Results: All of the group 1 patients were treated with simple lesion coverage while different stenting techniques
were used in group 2 (cross-over: 44.8%, T: 6.7%, kissing: 37.8%, and crush techniques: 11.1%). The 8-month
quantitative angiographic findings and in-hospital and 2 year rates of major adverse cardiac events (MACE)
were compared between the 2 groups. Although angiographic success and in-hospital MACE rates were similar
in both groups with 1 cardiac death due to acute stent thrombosis in group 2, at 2-year follow-up, the MACE
rate was significantly higher in group 2 than in group 1 at 2 years (22.2% vs 2.6%, respectively, P = 0.008).
Coronary angiography revealed a significantly higher binary restenosis rate in group 2 compared with group 1
(20% vs 0%, respectively, P = 0.003).
Conclusions: Interventional treatment using SES in left main lesions showed favorable short-term and long-
term outcomes in selected patients with lesion location being an important determinant of clinical and
angiographic outcomes.
Keimyung Author(s)(Kor)
조윤경
김형섭
남창욱
허승호
김권배
김윤년
Publisher
School of Medicine
Citation
Ung Kim et al. (2009). Two-Year Outcomes of the
Sirolimus-Eluting Stent According to
Unprotected Left Main Lesion. Clinical Cardiology, 32(6), 332–336. doi: 10.1002/clc.20563
Type
Article
ISSN
0160-9289
Source
http://onlinelibrary.wiley.com/doi/10.1002/clc.20563/epdf
DOI
10.1002/clc.20563
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35487
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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