Uric Acid as Prognostic Marker in Advanced Nonischemic Dilated Cardiomyopathy: Comparison With N-Terminal Pro B-Type Natriuretic Peptide Level

Authors
Hyungseop KimHong-Won ShinJihyun SonHyuck-Jun YoonHyoung-Seob ParkYun-Kyeong ChoChoon-Duk HanChang-Wook NamSeung-Ho HurYoon-Nyun KimKwon-Bae Kim
Department
Dept. of Internal Medicine (내과학)
Issue Date
2010
Citation
Congest Heart Failure, Vol.16(4) : 153-158, 2010
ISSN
1527-5299
Abstract
Although uric acid (UA) level has been associated with an increased risk of cardiovascular events, it is unclear whether UA can provide greater prognostic information than N-terminal pro B-type natriuretic peptide (NT-proBNP) in advanced heart failure with nonischemic dilated cardiomyopathy (DCM). UA and NT-proBNP values were obtained from a total of 122 DCM patients. Development of clinical events during follow-up was defined as the composite of cardiac death and readmission for heart failure. During follow-up, there were 18 cardiac events. UA and NT-proBNP values were significantly higher in patients with events. The receiver operating characteristics curve showed the area under the curve for UAwas greater than that forNT-proBNP. On multivariate analysis, UA remained the only independent predictor of prognosis. UA concentrations 8.7 mg⁄ dL rather than NT-proBNP 3800 pg⁄mL were associated with significantly decreased event-free survival. The authors’ findings demonstrated that UA value could be an informative predictor in nonischemic DCM
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/35534
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
김형섭; 윤혁준; 박형섭; 조윤경; 남창욱; 허승호; 김윤년; 김권배
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