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Uric Acid as Prognostic Marker in Advanced Nonischemic Dilated Cardiomyopathy: Comparison With N-Terminal Pro B-Type Natriuretic Peptide Level

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Affiliated Author(s)
김형섭윤혁준박형섭조윤경남창욱허승호김윤년김권배
Alternative Author(s)
Kim, Hyung SeopYoon, Hyuck JunPark, Hyoung SeobCho, Yun KyeongNam, Chang WookHur, Seung HoKim, Yoon NyunKim, Kwon Bae
Journal Title
Congest Heart Failure
ISSN
1527-5299
Issued Date
2010
Abstract
Although uric acid (UA) level has been associated with an increased risk of cardiovascular
events, it is unclear whether UA can provide greater prognostic information than
N-terminal pro B-type natriuretic peptide (NT-proBNP) in advanced heart failure with nonischemic
dilated cardiomyopathy (DCM). UA and NT-proBNP values were obtained from
a total of 122 DCM patients. Development of clinical events during follow-up was defined
as the composite of cardiac death and readmission for heart failure. During follow-up,
there were 18 cardiac events. UA and NT-proBNP values were significantly higher in
patients with events. The receiver operating characteristics curve showed the area under
the curve for UAwas greater than that forNT-proBNP. On multivariate analysis, UA
remained the only independent predictor of prognosis. UA concentrations 8.7 mg⁄ dL
rather than NT-proBNP 3800 pg⁄mL were associated with significantly decreased
event-free survival. The authors’ findings demonstrated that UA value could be an
informative predictor in nonischemic DCM
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Hyungseop Kim et al. (2010). Uric Acid as Prognostic Marker in Advanced Nonischemic Dilated
Cardiomyopathy: Comparison With N-Terminal Pro B-Type
Natriuretic Peptide Level. Congest Heart Failure, 16(4), 153–158. doi: 10.1111/j.1751-7133.2010.00144.x
Type
Article
ISSN
1527-5299
DOI
10.1111/j.1751-7133.2010.00144.x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35534
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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