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dc.contributor.authorHee Yeon Lee-
dc.contributor.authorJi Hyung Hong-
dc.contributor.authorJae Ho Byun-
dc.contributor.authorHee-Jun Kim-
dc.contributor.authorJin Young Kim-
dc.contributor.authorKi Hyang Kim-
dc.contributor.authorJina Yun-
dc.contributor.authorJung A Kim-
dc.contributor.authorKwonoh Park-
dc.contributor.authorHyo Jin Lee-
dc.contributor.authorJung Lim Lee-
dc.contributor.authorYoung-Woong Won-
dc.contributor.authorIl Hwan Kim-
dc.contributor.authorWoo Kyun Bae-
dc.contributor.authorKyong Hwa Park-
dc.contributor.authorDer-Sheng Sun-
dc.contributor.authorSun Kyung Baek-
dc.contributor.authorSuee Lee-
dc.contributor.authorMin-Young Lee-
dc.contributor.authorGuk Jin Lee-
dc.contributor.authorSook Hee Hong-
dc.contributor.authorYun Hwa Jung-
dc.contributor.authorHo Jung An-
dc.date.accessioned2020-05-04T16:30:13Z-
dc.date.available2020-05-04T16:30:13Z-
dc.date.issued2020-
dc.identifier.citationCancer Research and Treatment, Vol.52(1) : 277-283, 2020-
dc.identifier.issn2005-9256-
dc.identifier.otheroak-2020-0002-
dc.identifier.urihttp://kumel.medlib.dsmc.or.kr/handle/2015.oak/42542-
dc.description.abstractPurpose: The purpose of this study was to evaluate clinical characteristics and treatment pattern of ovarian clear cell carcinoma (OCCC) in Korea and the role of adjuvant chemotherapy in early-stage. Materials and Methods: Medical records of 308 cases of from 21 institutions were reviewed and data including age, performance status, endometriosis, thromboembolism, stage, cancer antigen 125, treatment, recurrence, and death were collected. Results: Regarding stage of OCCC, it was stage I in 194 (63.6%), stage II in 34 (11.1%), stage III in 66 (21.6%), and stage IV in 11 (3.6%) patients. All patients underwent surgery. Optimal surgery (residual disease ≤ 1 cm) was achieved in 89.3%. Majority of patients (80.5%) received postoperative chemotherapy. The most common regimen was taxane-platinum combination (96%). Median relapse-free survival (RFS) was 138.5 months for stage I, 33.4 for stage II, 19.3 for stage III, and 9.7 for stage IV. Median overall survival (OS) were not reached, 112.4, 48.7, and 18.3 months for stage I, II, III, and IV, respectively. Early-stage (stage I), endometriosis, and optimal debulking were identified as favorable prognostic factors for RFS. Early-stage and optimal debulking were also favorable prognostic factors for OS. Majority of patients with early-stage received adjuvant chemotherapy. However, additional survival benefit was not found in terms of recurrence. Conclusion: Majority of patients had early-stage and received postoperative chemotherapy regardless of stage. Early-stage and optimal debulking were identified as favorable prognostic factors. In stage IA or IB, adding adjuvant chemotherapy did not show difference in survival. Further study focusing on OCCC is required.-
dc.description.statementofresponsibilityopen-
dc.publisherSchool of Medicine (의과대학)-
dc.rightsBY_NC_ND-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/kr-
dc.subjectOvarian epithelial carcinoma-
dc.subjectClear cell adenocarcinoma-
dc.subjectKorea-
dc.subjectAdjuvant chemotherapy-
dc.titleClinical Characteristics of Clear Cell Ovarian Cancer: A Retrospective Multicenter Experience of 308 Patients in South Korea-
dc.typeArticle-
dc.contributor.localauthor김진영-
dc.contributor.alternativelocalauthorKim, Jin Young-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.citation.volume52-
dc.citation.number1-
dc.citation.startpage277-
dc.citation.titleCancer Research and Treatment-
dc.citation.endpage283-
dc.identifier.doi10.4143/crt.2019.292-
dc.identifier.urlhttps://www.e-crt.org/journal/view.php?number=3023-


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