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수종 자궁수축제의 마우스의 적출자궁 수축력에 미치는 효과의 비교

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Author(s)
이상엽이만기주영은
Journal Title
Keimyung Medical Journal
Issued Date
1983
Volume
2
Issue
1
Abstract
The response of the isolated uterus from pregnant (gestational period less than 10 days) and nonpregnant mouse to uterine stimulants, oxytocin, prostaglandin F₂α (PGF₂α )and ergonovine, was observed in low calcium Tyrode's solution. Potency was represented by the value of pD₂ which is defined as the negative logarithm of the concentration producting half- maximal response to each drug. In the non-pregnant uterus, the pD₂ values of oxytocin, PGF₂α, and ergonovine were 8.86, 6.76, and 6.70, respectively. In the pregnant uterus, the values were 8.45, 7.50, and 7.75, respectively. A maximal response produced by oxytocin was similar to that by PGF₂α in both pregnant and nonpregnant uterus. However, the maximal response to ergonovine in the nonpregnant uterus was one-twenty fifth the response to oxytocin and PGF₂α, and in the pregnant uterus it was a half the response to them.
Alternative Title
Comparison of Effect of Uterine Stimulants on Isolated Mouse Uterus
Publisher
Keimyung University School of Medicine
Citation
이상엽 et al. (1983). 수종 자궁수축제의 마우스의 적출자궁 수축력에 미치는 효과의 비교. Keimyung Medical Journal, 2(1), 54–58.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14305
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1983
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