쥐의 성장에 따른 지질합성속도의 변화

Abstract

To investigate the changes of lipid synthesis in adipose tissue, radioactive acetic acid was administered to weaned rat, fed with 12%-lipid diet or 45% butter of diet. After 8 weeks of feeding. growth of 12%-normal lipid diet group was slightly more decreased than that of 45% butter fat diet group. Lipid content in abdominal adipose tissue was higher in high lipid diet group than control group. Rate of lipid biosynthesis in liver was slowly decrdased as aging in both group, on the otherhand, in adipose tissue the rate of lipid biosynthesis revealed maximum value at 12th weeks after birth, therafter decreased significantly. These findings are compatible with the view that the rate of lipid biosynthesis in both liver and adipose tissue decreases slowly as aging.