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식이성 지방의 함량과 종류가 흰쥐 Lipoprotein의 분획상에 미치는 영향

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Affiliated Author(s)
곽춘식
Alternative Author(s)
Kwak, Chun Sik
Journal Title
Keimyung Medical Journal
Issued Date
1984
Abstract
Effect of a high level and types of dietary fat on serum lipoproteins was investigated in Sprague-Dawley rats weighing 60-65gm. The animals were divided into three groups and were fed 3 different fat diet: 12% calorie fat diet, 45% calorie-butter fat diet, and 45% calorie-corn oil diet. The diets were isoenergetic (4.4Kcal/gm), and were fed to the rats ad libitum for 12 weeks. Mean serum lipoprotein levels in mg/dl for the control group were 36.4±10.7: chylomicron, 15.9±5.2: VLDL, 26.2±4.7: LDL, and 93.3±18.7: HDL. The high corn oil diet did not significantly change the levels of serum lipoproteins except 1.5-fold increase in LDL. However, the high-butter fat diet showed 1.5-to 2-fold increase in serum levels of chylomicron. VLDL and LDL, but no change in HDL level. These result indicate that long-term feeding fo high-fat diet composed of primarily saturated fatty acid increases serum levels of lower dinsity fractions of lipoprotein.
Alternative Title
Effect of High-Fat Diet on Serum Lipoproteins in Rats
Department
Dept. of Biochemistry (생화학)
Publisher
Keimyung University School of Medicine
Citation
곽춘식 et al. (1984). 식이성 지방의 함량과 종류가 흰쥐 Lipoprotein의 분획상에 미치는 영향. Keimyung Medical Journal, 3(1), 22–26.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14332
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1984
1. School of Medicine (의과대학) > Dept. of Biochemistry (생화학)
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