절제위암조직에서의 중간대의 변화

Abstract

This study was conducted to investigate changes in the intermediate zone on the resected gastric cancer specimens from 117 patients for correlation between age group and intestinal metaplasia.

The results obtained were as follows:

Of the total 1X7 cases, normal intermediate zone was found in 38 cases (32.5%), and mild, moderate and severe atrophic intermediate zone were similar in distribution. There was a significant correlation of intermediate zone with age group above and below 5th decade (p <0.05).

The degree of intestinal metaplasia was correlated well with that of atrophy of the intermediate zone (p <0.05).

It was speculated that atrophy of the intermediate zone and intestinal metaplasia were correlated with gastric cancer and it is worth-while to pursue that these changes play role in the pathogenesis of gastric cancer.