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Waldeyer 편도환 림프종의 임상적 고찰

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Author(s)
송홍석허정욱
Keimyung Author(s)
Hur, Jung WookSong, Hong Suk
Department
Dept. of Internal Medicine (내과학)
Journal Title
Keimyung Medical Journal
Issued Date
1985
Volume
4
Issue
2
Abstract
A retrospective review is presented of 24 previously untreated patients with lymphoma of Walde-yer's ring(WR) between January 1972 through December 1984 at the Keimyung University. The incidence of WR involvement of non-Hodgkin's lymphoma was 11.1% and of Hodgkin's disease was 4.7%. The mean age was 48.8 years, with a male to female ratio of 1.7 : 1.0. On admission, neck mass was the most frequent symptom in 14 cases(58.3%) and sore throat, odyno-phagia, dysphagia, hoarseness and nasal stuffiness were commonly presented. The anatomical distribution of the growth within WR was as follow: tonsil, 75.0%; nasopharynx, 25.0%; base of tongue, 4.2%. Histiocytic architecture predominated (83.3%) and local-regional involvement (stage Ⅰand Ⅱ) occurred in 75% with this morphology. Other histologic pattern was 2 cases of diffuse poorly-differentiated lymphocytic, 1 case of nodular poorly-differentiated lymphocytic lymphoma and 1 case of Hodgkin's disease with all in advanced stage (stage Ⅲ and Ⅳ). All ofthe local-regional disease were treated by irradiation and 1 patient were treated in addition with combination chemotherapy. Advanced disease were treated initially by combination chemotherapy. Response rate (complete response plus partial response) of stage Ⅰ and Ⅱ was 60% and stage Ⅲ and Ⅳ was 50%.
저자들은 1972년 1월부터 1984년 12월 사이에 본원에 내원한 치료병력이 없는 Waldeyer 편도환을 침범한 림프종환자 24예를 분석검토하여 다음과 같은 결과를 얻었다. 연령은 14세에서 82세까지로 평균 48.8세였으며 남녀비는 1.7:1로 남자에서 많았다. 초진시의 증상은 경부종양이 14예(58.3%)로 가장 많았으며 인후통 12예(50%) 연하통 6예(25%) 연하곤란 5예(20.8%) 목쉼 및 비폐색이 각기 4예(16.7%)였다. 초진시의 이학적소견은 림프전종대가 19예(79.2%)로 경부 액와부 서혜부 쇄골상와림프길 순으로 빈번하였으며, Waldeyer 편도환의 침범은 비호지킨 림프종의 11.1% 호지킨병의 4.7%에서 동반되었으며 부위별로는 편도가 18예(75%) 비인두가 6예(25%) 설기저부가 1예(4.2%)였다. 조직학적분류를 보면 조직구형이 20예(83.3%)로 대부분을 차지하였으며, diffuse poorly-differentiated lymphocytic형 2예, nodular poorly-differentiated lymphocytic형 1예 그리고 호지킨병이 1예였다. 병기별로는 stageⅠ,Ⅱ가 15예(62.5%)로 모두 조직구형이었으며 stageⅢ,Ⅳ가 9예(37.5%)였고 B형은 4예(16.7%)로 진행된 병기에서 동반율이 높았다. 치료는 stageⅠ,Ⅱ 9예는 방사선요법, stageⅢ,Ⅳ 6예는 다제병합화학요법 그리고 stageⅡ,Ⅲ,Ⅳ 각 1예는 병용치료를 시행하였으며 이 중 stageⅠ,Ⅱ의 6예(60%)외 stageⅢ,Ⅳ의 4예(50%)에서 부분적관해 이상의 반응을 나타내었다.
Alternative Title
Malignant Lymphoma with Involvement of Waldeyer’s Ring : A Clinical Study of 24 Cases
Keimyung Author(s)(Kor)
송홍석
허정욱
Publisher
Keimyung University School of Medicine
Citation
송홍석 and 허정욱. (1985). Waldeyer 편도환 림프종의 임상적 고찰. Keimyung Medical Journal, 4(2), 242–247.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14403
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1985
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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