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흰쥐 담즙울체간의 Plasma Membrance, Mitochondria 및 Microsome의 5'-Nucleotidase와 Gamma-Glutamyl Transpeptidase의 활성치

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Author(s)
곽춘식김여희문교철
Keimyung Author(s)
Kwak, Chun SikKim, You HeeMun, Kyo Cheol
Department
Dept. of Biochemistry (생화학)
Journal Title
Keimyung Medical Journal
Issued Date
1987
Volume
6
Issue
1
Abstract
Changes in the activities of the following have been studied over a period of forty two days following the ligation of common bile duct in rats: plasma membrane, microsomal, mitochondrial, nuclear and cytosolic 5'-nucleotidase and gamma-glutamyl transpeptidase of cholestatic liver. The activities of alkaline phosphatase in the subcellular fractions of cholestatic liver were also measured. The activities of microsomal and cytosolic 5'-nucleotidase in cholestatic liver markedly elevated between the second and the forty-second days of the operation. However, the plasma membrane, mitochondrial and nuclear5'-nucleotidase activities in the cholestatic liver showed a substantial decrease from three days to forty two days after the ligation of common bile duct. The activities of hepatic microsomal, cytosolic, plasma membrane, mitochondrial and nuclear gtamma-glutamyl transpeptidase drastically increased throughout the experiments. The activities of microsomal and cytosolic alkaline phosphatase in the cholestatic liver strikingly increased during the forty two days following the operation, but the plasma-membrane bound alkaline phosphatase in the cholestatic liver had a significant diminution after the ligation of common bile duct.
Alternative Title
5'-Nucleotidase and Gamma-Glutamyl Transpeptidase Activities in the Cholestatic Rat Liver Plasma Membranes, Mitochondria and Microsomes
Keimyung Author(s)(Kor)
곽춘식
김여희
문교철
Publisher
Keimyung University School of Medicine
Citation
곽춘식 et al. (1987). 흰쥐 담즙울체간의 Plasma Membrance, Mitochondria 및 Microsome의 5'-Nucleotidase와 Gamma-Glutamyl Transpeptidase의 활성치. Keimyung Medical Journal, 6(1), 67–76.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14462
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1987
1. School of Medicine (의과대학) > Dept. of Biochemistry (생화학)
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