Cryptococcus 뇌막염 4례

Abstract

Four cases of cryptococcal meningitis were experienced in Keimyung University Hospital during 11 years periods. These patients were one pregnant woman, one man who had liver cirrosis and diabetes mellitus and two healthy men. After admission, all four patients were treated with antituberculous agent under the impression of tuberculous meningitis, but no clinical improvement was achieved. Later, Crytococcus neoformans was identified in CSF by India ink preparation or Sabouraud media culture, after then one patient was treated with combination of amphotericin B and 5-fluorocytosine and achieved much clinical and laboratory improvement. Unfortunately other three patients were not followed. The authors experienced four cases of crytococcal meningitis and herein presenting our experience and literature were reviewed.