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지속적 과환기에 따른 뇌척수액과 혈액가스치의 변화

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Author(s)
전재규김진모
Keimyung Author(s)
Cheun, Jae KyuKim, Jin Mo
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
Keimyung Medical Journal
Issued Date
1987
Volume
6
Issue
2
Abstract
Acid-base balance in CSF have been reported by a number of groups during past 20 years. CSF contained only negligible concentration of buffer anion other than HCO₃. Acid-base balance in the CSF depend mainly on arterial PCO₂ because arterial CO₂ diffuses easily into the blood brain barrier to form H₂CO₃ in CSF. This study was undertaken to observe the changes of PH, PCO₂,base excess and actual HCO₃, values in CSF in the controlled hyperventilation. The changes in pH and actual HCO₃, Base Excess in CSF of anesthetized , non-curarized 7 dogs during continous controlled hyperventilation were compared with those changes when the blood acid-base parameters were kept at normal level. Both groups were mechanically ventilated to maintain a constant PaCO₂ 20 torr. The PH , PCO₂, actual「HCO₃」,and Base Excess in cisternal CSF and arterial blood were determined at normal condition as a control group shortly after induction of controlled hyperventilation thereafter, were measured at 0.5, 1.0, 1.5, 3.5, 5.5 and 7.5 hours. The results were as follows : 1) The pH of CSF in the controlled group was significantly lower than that of arterial blood and the Pcsf CO₂ was 10 torr higher than PaCO₂. 2) The standard 「HCO₃」and BE seemed to be compenasting after continous hyperventilation of 3.5 hours and reached to the values of the controlled group. 3) The Pcsf CO₂ decreased rapidly during hyperventilation and than, was maintained in a parallel distance with PaCO₂.
Alternative Title
Changes of Gas Values in the CSF by Continuous Controlled Hyperventilation
Keimyung Author(s)(Kor)
전재규
김진모
Publisher
Keimyung University School of Medicine
Citation
전재규 and 김진모. (1987). 지속적 과환기에 따른 뇌척수액과 혈액가스치의 변화. Keimyung Medical Journal, 6(2), 373–378.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14500
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1987
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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