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유암조직에서 단세포군항체를 이용한 면역세포화학법에 의한 에스트로겐 수용체의 측정

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Author(s)
김인호손수상강중신이상숙
Keimyung Author(s)
Kim, In HoSohn, Soo SangKang, Joong ShinLee, Sang Sook
Department
Dept. of Surgery (외과학)
Dept. of Pathology (병리학)
Journal Title
Keimyung Medical Journal
Issued Date
1990
Volume
9
Issue
4
Keyword
Breast cancerEstrogen receptor
Abstract
Estrogen receptor(ER) is an unique protein that specifically binds estrogens in tissue that responds to this hormone. In order for tissue to recognize estrogens, it is considered necessary for ER to be present. Receptor assay can be used in prediction of response of hormonal therapy in treatment of breast cancers. Immunocytochemical assays(ICA) involve localization and staining of ER in tissues or cell preparations using monoclonal antibodies. Frozen sections from 13 human breast carcinomas were examined for the presence and distribution of ER-containing tumor cells using Abbott ER-ICA monoclonal antibodies and immunoperoxidase technique. Estrogen receptor was localized only in the nuclei in breast tumor cells in 6 cases. Serveral staining patterns were observed. Thus, an immunocytochemical assay for estrogen receptor may provide additional information for identifying hormonally responsive breast cancers.
Alternative Title
An
Immunocytochemical Assay of Estrogen Receptor in Breast Cancers Using Monoclonal Antibodies
Keimyung Author(s)(Kor)
김인호
손수상
강중신
이상숙
Publisher
Keimyung University School of Medicine
Citation
김인호 et al. (1990). 유암조직에서 단세포군항체를 이용한 면역세포화학법에 의한 에스트로겐 수용체의 측정. Keimyung Medical Journal, 9(4), 439–444.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14657
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1990
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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