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흰쥐 재생간에서의 Glucose-6-Phosphate Isomerase 및 Fructose-1,6-Bisphosphate Aldolase의 활성도

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Author(s)
김일경곽춘식문교철
Keimyung Author(s)
Mun, Kyo CheolKwak, Chun Sik
Department
Dept. of Biochemistry (생화학)
Institute for Medical Science (의과학 연구소)
Journal Title
Keimyung Medical Journal
Issued Date
1996
Volume
15
Issue
2
Keyword
Fructose-l6-bisphosphate aldolaseGlucose-6-phosphate isomeraseRegenerating rat liver
Abstract
This study was made in order to understand the changes involved with glucose-6-phsophate isomerase(GPI) and fructose-1, 6-bisphosphate aldolase(ALS) activities in regenerating rat liver Cytosolic, mitochondrial and microsomal GPI and ALS activities were determined in regenerating liver tissue following 70%(median and left lateral lobes) partial hepatectomy in rats for a period of ten days The activities of these enzymes in serum were also measured.
The activities of cytosolic and microsomal GPI in regenerating rat liver tissue showed a significant increase from the twelfth hour to the sixth day, and the from twelfth hour to the first day, respectively, following the partial hepatectomy. However, the mitochondrial GPI activity did not change
The activities of both cytosolic and mitochondrial ALS m regenerating rat liver tissue showed a significant increase
from the first day to the second day following the partial hepatectomy. However, microsomal ALS in regenerating liver tissue increased significantly from the twelfth hour to the second day following the partial hepatectomy.
The activities of both GPI and ALS m rat serum showed a significant increase from the twelfth hour to the third day following the partial hepatectomy.
In view of the above results, the presence of both GPI and ALS in regenerating rat liver suggest the enzymes increase their biosynthesis tn the regenerating stage
Alternative Title
Glucose-6-Phosphate
Isomerase and Fructose-1,6-Bisphosphate Aldolase Activities in Regenerating Rat Liver after Partial Hepatectomy
Keimyung Author(s)(Kor)
문교철
곽춘식
Publisher
Keimyung University School of Medicine
Citation
김일경 et al. (1996). 흰쥐 재생간에서의 Glucose-6-Phosphate Isomerase 및 Fructose-1,6-Bisphosphate Aldolase의 활성도. Keimyung Medical Journal, 15(2), 111–118.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14969
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1996
1. School of Medicine (의과대학) > Dept. of Biochemistry (생화학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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