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Cyclosporin에 의한 치은증식증의 치험 2례

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Author(s)
장학원김종배박효상김창환이용규최봉주
Keimyung Author(s)
Lee, Yong GyooPark, Hyo SangKim, Jong Bae
Department
Dept. of Dentistry (치과학)
Journal Title
Keimyung Medical Journal
Issued Date
1997
Volume
16
Issue
2
Keyword
치과학CYCLOSPORIN치은증식증CyclosporinGingival Hyperplasia
Abstract
Cyclosporin is a relatively new immunosuppressive agent which has been used to prevent organ transplant rejection, to treat type-I diabetes mellitus and several other autoimmune disorders. It is anticipated that the therapeutic use of cyclosporin will increase progressively in the future to treat numerous other disorders. As its clinical use broadens, it will needed for health professionals to be familiar with the beneficial effects as well as some of the undesirable side effects of cyclosporin therapy. A side effect of this drug in dentistry appears to be pronounced gingival hyperplasia. Cyclosporin induced gingival hyperplasia is indistinguishable from gingival hyperplasia induced by phenytoin and nifedipine in clinical and histopathologic finding.
We experienced two cases of gingival hyperplasia secondary to cyclosporin therapy in patients, 48-year old & 28-year old females who received a kidney allograft transplant. Clinical examinations revealed a severely overgrown and inflammed gingiva. Surgical excision of the excess tissue was accomplished under local anesthesia. On follow-up check, gingival hyperplasia in a 48-year old patient whose oral hygiene was very poor showed successive recurrence after three times surgical excision, another patient who could control oral hygiene thoroughly showed good healing.
Conclusively, it seems to be very important to control oral hygiene thoroughly to decrease occurrence and recurrence of cyclosporin-induced gingival hyperplasia.
Alternative Title
Cyclosporin-
induced Gingival Hyperplasia : Case Report
Keimyung Author(s)(Kor)
이용규
박효상
김종배
Publisher
Keimyung University School of Medicine
Citation
장학원 et al. (1997). Cyclosporin에 의한 치은증식증의 치험 2례. Keimyung Medical Journal, 16(2), 256–265.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15029
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1997
1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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