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급성 편두통에 대한 피하용 Sumatriptan의 효과

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Author(s)
임정근이형이성룡이상도박영춘
Keimyung Author(s)
Lim, Jeong GeunLee, HyungYi, Sang DoPark, Young ChunLee, Seong Ryong
Department
Dept. of Neurology (신경과학)
Dept. of Pharmacology (약리학)
Institute for Medical Science (의과학 연구소)
Journal Title
Keimyung Medical Journal
Issued Date
1998
Volume
17
Issue
1
Keyword
MigraineSumatriptan
Abstract
Migraine headache is thought to be associated with a dilatation of cranial blood vessels and an accompanying localized sterile inflammatory response. Sumatriptan, a selective agonist of 5-hydroxytryptamine receptors, blocks these phenomena. The efficacy and safety of sumatriptan in migraine were evaluated in this study. Twenty-six patients with 1 to 2 degree acute migraine were treated with a self-injection of 6mg Sumatriptan at home The outcome measures were the relief of headache and side effects within 2 hours of injection. Eighteen patients had migraine without aura, and the other eight had migraine with aura. Migraine attacks were improved in 75.6% (34 of 45 attacks) within 2 hours after sumatriptan injection. The rate of improvement was 80.8% (21 of 26 attacks) in first attacks and 68.4% (13 of 19 attacks) in second attacks. The efficacy of sumatriptan had no differences between migraine without aura and with aura. Adverse events were experienced by 34.6% of the patients. Most of them were minor and transient.
Therefore subcutaneous sumatriptan self-injection is an effective treatment in migraine attacks. The side effects are minor and transient.
Alternative Title
Treatment of Acute Migraine with Subcutaneous Sumatriptan
Keimyung Author(s)(Kor)
임정근
이형
이상도
박영춘
이성용
Publisher
Keimyung University School of Medicine
Citation
임정근 et al. (1998). 급성 편두통에 대한 피하용 Sumatriptan의 효과. Keimyung Medical Journal, 17(1), 43–48.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15063
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1998
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Pharmacology (약리학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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