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알츠하이머 및 혈관성 치매환자에서 L-Acetyl-Carnitine의 효과

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Author(s)
이형김태완임정근이상도박영춘
Keimyung Author(s)
Lee, HyungLim, Jeong GeunYi, Sang DoPark, Young Chun
Department
Dept. of Neurology (신경과학)
Institute for Medical Science (의과학 연구소)
Journal Title
Keimyung Medical Journal
Issued Date
1998
Volume
17
Issue
1
Keyword
DementiaL-acety卜carnitine
Abstract
A open clinical trial was conducted in order to evaluated the clinical efficacy and safety of L-acetyl-carnitine in patients with Alzheimer or vascular dementia.
18 patients were enrolled into this trial.
The efficacy of the drugs was evaluated by itemized neurolgic check list in each months.
The results were summarized as follows.
1. There were significant improvement of psychotic symptoms in 4 weeks and 12 weeks.
2. In Hasegawa dementia scale, the average scores of 12 weeks were significantly higher than the scores of base line and 4 weeks, respectively.
3. In MMSE-K, the average scores of 12 weeks were significantly higher than the scores of base line and 4 weeks, respectively.
4. The drug was safe but mild gastrointestinal disturbance was observed very rarely as adverse reaction.
The administration of L-acetyl-carnitine had significantly improvement of cognitive and psychotic symptoms of patients with Alzheimer or vascular dementia. The side effects were minor and transient.
Alternative Title
Effect of L - Acetyl -
Carnitine in Patients with Alzheimer or Vascular Dementia
Keimyung Author(s)(Kor)
이형
임정근
이상도
박영춘
Publisher
Keimyung University School of Medicine
Citation
이형 et al. (1998). 알츠하이머 및 혈관성 치매환자에서 L-Acetyl-Carnitine의 효과. Keimyung Medical Journal, 17(1), 72–78.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15066
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1998
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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