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부분 간이식을 시행한 실험견의 이식전후의 혈역동적 변화

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Author(s)
조원현강구정김형태
Keimyung Author(s)
Cho, Won HyunKim, Hyoung TaeKang, Koo Jeong
Department
Dept. of Surgery (외과학)
Institute for Medical Science (의과학 연구소)
Journal Title
Keimyung Medical Journal
Issued Date
1998
Volume
17
Issue
3
Keyword
Liver transplantationHemodynamic changes
Abstract
In order to compare the hemodynamic changes that occurred during the conventional whole liver transplantation, we performed piggyback type segmental liver transplantation in 6 adult dogs and monitored hemodynamic changes during the whole operative procedures. During the anhepatic period, only left hepatic vein was clamped but the influx of the inferior vena caval flow was completely preserved. The mean arterial pressure, cardiac output and pulmonary flow were decreased moderately but restored slowly after declamping of the portal vein. But we couldn't observe post-reperfusion syndrome in this procedure. Arterial blood gas analysis showed decreased level of potassium and ionized calcium during the anhepatic period with severe acidosis but slowly corrected after declamping of portal vein. The prolonged aPTT was continued during the operation but should consider the usage of the heparin during the vascular clamp. Therefore, we believe that piggyback procedure seems to minimize the hemodynamic changes during the segmental liver trandplantation. To detect other factors that disturb the coagulation mechanism, coagulation factor study will be necessary.
Alternative Title
Hemodynamic
Changes During the Segmental Liver Transplantation in Experimental Dogs
Keimyung Author(s)(Kor)
조원현
김형태
강구정
Publisher
Keimyung University School of Medicine
Citation
조원현 et al. (1998). 부분 간이식을 시행한 실험견의 이식전후의 혈역동적 변화. Keimyung Medical Journal, 17(3), 345–353.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15094
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1998
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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