To evaluate the prevalence of antibody to hepatitis C virus (anti-HCV) in patients with open heart surgery we did a prospective study of alanine aminotransferasa (ALT) before operation and one, three and six months after operation and of anti-HCV one and six months after operation in 61 patients who had taken open-heart surgery. No significant change was noted in liver function test before and after operation. One(1.6%) of 61 patients was anti-HCV positive after operation. Hepatitis C virus is the major cause of post-transfusion hepatitis in Korea and in the world. But the positive rate of anti-HCV was very low in our study. It is uncertain whether the cause is due to false negativity, failure of detection of anti-HCV or low positivity of anti-HCV of dornated blood.
Alternative Title
Antibody to Hepatitis C Virus in Open Heart Surgery Patients