계명대학교 의학도서관 Repository

Classification of Amyloidosis by Immunohistochemical Method and Potassium Permanganate Reaction: Correlation Between Morphology, Chemical Types and Clinical Features

Metadata Downloads
Author(s)
박관규박성배김현철
Keimyung Author(s)
Park, Kwan KyuPark, Sung BaeKim, Hyun Chul
Department
Dept. of Pathology (병리학)
Dept. of Internal Medicine (내과학)
Journal Title
Keimyung Medical Journal
Issued Date
2000
Volume
19
Issue
1
Keyword
AA amyloidosisPotassium permanganateImmunohistochemistryAL amyloidosis
Abstract
Systemic amyloidosis is a rare disorder, which usually occurs in aged people with a poor prognosis. Forty-five patients with amyloidosis were studied by light microscopy with Congo red staining, potassium permanganate reaction and immunohistochemistry. The biopsy sites were abdominal fat, rectum, lung, bone marrow, liver, pleura, duodenum, gallbladder, colon, oral cavity, larynx, thyroid and skin. The patients were classified according to immunohisto-chemistry and Congo red staining results after potassium permanganate treatment. Thus, 21 of 45(46.7%) cases were classified as AA (amyloid A protein), and 24(53.3%) cases were classified as AL(amyloid light chain) amyloidosis. This study suggests that the association of these two techniques, potassium permanganate reaction and immunohistochemical stain, is more reliable than clinical data alone in distinguishing between AA and AL amyloidosis.
Keimyung Author(s)(Kor)
박관규
박성배
김현철
Publisher
Keimyung University School of Medicine
Citation
박관규 et al. (2000). Classification of Amyloidosis by Immunohistochemical Method and Potassium Permanganate Reaction: Correlation Between Morphology, Chemical Types and Clinical Features. Keimyung Medical Journal, 19(1), 1–10.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15181
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2000
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.