사이클로스포린에 의해 유발된 가역적 파킨슨증 1례
- Author(s)
- 최종환; 이현아; 이형; 임정근; 이상도
- Keimyung Author(s)
- Yi, Hyon Ah; Lee, Hyung; Lim, Jeong Geun; Yi, Sang Do
- Department
- Dept. of Neurology (신경과학)
- Journal Title
- Keimyung Medical Journal
- Issued Date
- 2001
- Volume
- 20
- Issue
- 1
- Keyword
- Parkinsonism; Cyclosporine A
- Abstract
- Cyclosporine A (CsA) widely
used for immunosuppression has been associated with various neurologic side effects including postural tremor, seizure, headache, encephalopathy and Parkinsonism. However, there has been no report describing CsA induced Parkinsonism in Korea. We described a 41-year old woman with cyclosporine induced Parkinsonism characterized by bradykine- sia, cogwheel rigidity, postural and resting tremor. She had been received CsA for a few months to prevent rejection after renal transplantation. There were high signal intensities in both putamen, sub-thalamic and caudate nuclei on T2-weighted MRI. After discontinued CsA, her symptoms were disappeared.
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