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14C-요소 호기검사를 이용한 Helicobacter pylori의 3제요법과 2제요법의 제균율 분석

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Affiliated Author(s)
김상현안성훈전석길
Alternative Author(s)
Kim, Sang HyonAhn, Sung HoonZeon, Seok Kil
Journal Title
Keimyung Medical Journal
Issued Date
2002
Keyword
Helicobacter pylori14C-urea breath testGastric ulcerDuodenal ulcer
Abstract
Helicobacter pylori (H. pylori) infection is associated with chronic
active gastritis, duodenal and gastric ulcers, gastric adenocarcinoma, and gastric
lymphoma. The eradication of H. pylori not only results in the healing of ulcer but
also reduces recurrence of peptic ulcer. Using 14C-urea breath test, we compared
the efficacy of omeprazole-based triple therapy and dual therapy in patients with
H. pylori-positive peptic ulcer. Seventy nine H. pylori-positive patients with peptic
ulcer were enrolled and randomly divided into two groups. Fifty nine patients
received triple therapy (omeprazole, clarithromycin and amoxicillin) for 7 days
and twenty patients received dual therapy (omeprazole and clarithromycin) for 14
days. The eradication of H. pylori was assessed by 14C-urea breath test 4-8 weeks
after the completion of each therapy. The overall eradication rate of H. pylori,
using 14C-urea breath test, was 88.1% in the triple therapy group and 35% in the
dual therapy group, therefore the eradication rate of triple therapy was higher
than that of dual therapy.
Alternative Title
Analysis of
Eradication Rate of Helicobacter Pylori by
Treatment Regimen of Triple Therapy and Dual Therapy
Using 14C-Urea Breath Test
Department
Dept. of Internal Medicine (내과학)
Dept. of Nuclear Medicine (핵의학)
Publisher
Keimyung University School of Medicine
Citation
이승현 et al. (2002). 14C-요소 호기검사를 이용한 Helicobacter pylori의 3제요법과 2제요법의 제균율 분석. Keimyung Medical Journal, 21(1), 76–82.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15242
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2002
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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