전신성 홍반성 루프스에 동반된 횡단선 척수염 1례

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease associated with variable symptoms in many organs. Involvement of central nervous system in SLE is a relatively common complication. However, transverse myelitis is a rare and late complication of SLE and its prognosis is very poor, resulting in death or severe neurologic sequelae. We report a case of transverse myelitis who was diagnosed as SLE before the onset of neurologic symptoms. Transverse myelitis was diagnosed, based on the clinical presentation and MRI findings. This patient indicated that transverse myelitis could be a relatively early manifestation of SLE. We treated the patient with pulse methyprednisolone followed by cyclophosphamide, However, the treatment did not improve clinical condition of the patient.