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Adriamycin에 의해 유발된 가역적인 심근병증 1례

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Author(s)
장용석조주연허지안도영록송홍석
Keimyung Author(s)
Do, Young RokSong, Hong SukCho, Ju Yeon
Department
Dept. of Dentistry (치과학)
Dept. of Internal Medicine (내과학)
Journal Title
Keimyung Medical Journal
Issued Date
2002
Volume
21
Issue
1
Keyword
AdriamycinCardiomyopathy
Abstract
Adriamycin is a chemotherapeutic agent highly effective against a
wide range of neoplasms. A primary limiting factor to the administration of this
drug is a cardiotoxicity, which frequently develops when the cumulative dose
exceeds 500 mg/m2. Cardiomyopathy, which may develop even after a year of discontinuation
of adriamycin therapy, is though to be rapidly progressive and unresponsive
to standard cardiac therapy. We experienced a case of adriamycininduced
cardiomyopathy. A 53-year-old male patient who received 337 mg/m2 of
adriamycin experienced congestive heart failure at 5 years since the completion of
the therapy. Endomyocardial biopsy showed vacuolization of myocytes and focal
fibrotic areas. The patient responded to diuretics, inotrophic agents, and an
angiotensin converting enzyme inhibitors, and resolution of left ventricular dysfunction
was verified by plain chest radiography and echocardiography.
Alternative Title
A Case of Reversible
Adriamycin-Induced Cardiomyopathy
Keimyung Author(s)(Kor)
도영록
송홍석
조주연
Publisher
Keimyung University School of Medicine
Citation
장용석 et al. (2002). Adriamycin에 의해 유발된 가역적인 심근병증 1례. Keimyung Medical Journal, 21(1), 117–121.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15248
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2002
1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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