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간경변증 환자에서 심혈관계 자율신경 기능이상

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Author(s)
김혜순김미정조광범황재석안성훈박승국
Keimyung Author(s)
Kim, Hye SoonCho, Kwang BumHwang, Jae SeokAhn, Sung HoonPark, Soong Kook
Department
Dept. of Internal Medicine (내과학)
Journal Title
Keimyung Medical Journal
Issued Date
2003
Volume
22
Issue
1
Keyword
Autonomic dysfunctionIndocyanine green testLiver cirrhosis
Abstract
Autonomic neuropathy has
been reported in association with liver
cirrhosis. Cardiovascular autonomic nerve function was tested in fourteen healthy
control subjects and twenty-six liver cirrhosis patients. Heart rate response to Valsalva maneuver and to deep breathing, and immediate heart rate response to standing were used to assess parasympathetic function. Blood pressure response
to standing and to sustained hand grip were used to assess sympathetic function. Cardiovascular autonomic dysfunction was diagnosed when at least one response of five tests was abnormal. The cirrhosis patients were also subdivided into two
groups according to the indocyanine green (ICG) secretion test abnormality (cut
off value 15%), and into three groups according to the Child-Pugh classification respectively. One (7%) of fourteen control subjects and fifteen (58%) of twenty-six cirrhosis patients showed evidence of cardiovascular autonomic dysfunction. One (17%) of six patients with normal ICG test, and fourteen (70%) of twenty patients with abnormal ICG test showed abnormal test results. Five (38%) of thirteen patients with Child-Pugh classification A, and ten (77%) of thirteen, patinets with Child-Pugh classification B and C showed cardiovascular autonomic dysfunction. These results show that cardiovascular autonomic dysfunction is, common in the liver cirrhosis patients, and parallels with disease severity.
Alternative Title
Cardiovascular
Autonomic Dysfunction in Patients with Liver Cirrhosis
Keimyung Author(s)(Kor)
김혜순
조광범
황재석
안성훈
박승국
Publisher
Keimyung University School of Medicine
Citation
김혜순 et al. (2003). 간경변증 환자에서 심혈관계 자율신경 기능이상. Keimyung Medical Journal, 22(1), 127–134.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15274
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2003
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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