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암 진단지표로서 MAGE의 특성

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Author(s)
박종욱
Keimyung Author(s)
Park, Jong Wook
Department
Dept. of Immunology (면역학)
Journal Title
Keimyung Medical Journal
Issued Date
2003
Volume
22
Issue
별호
Keyword
Cancer diagnosis markerMelanoma antigen gene
Abstract
The human MAGE A family encodes products that can be recognized by autologous cytotoxic T cells. Because MAGE genes are silent in most normal tissues except testis but are activated in a variety of neoplastic lesions, MAGE antigens represent ideal targets for cancer diagnosis and immunotherapy. MAGA A family consists of 12 subtypes, and there are high DNA homology between subtypes. Here, I discussed the importance of MAGE as cancer diagnosis marker and molecular methods for the detection of several MAGE subtypes together by RT-PCR using common primers.
Alternative Title
Characteristics of
MAGE as Cancer Diagnosis Marker
Keimyung Author(s)(Kor)
박종욱
Publisher
Keimyung University School of Medicine
Citation
박종욱. (2003). 암 진단지표로서 MAGE의 특성. Keimyung Medical Journal, 22(별호), 125–130.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15311
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2003
1. School of Medicine (의과대학) > Dept. of Immunology (면역학)
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