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신이식 후 발생한 악성종양

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Author(s)
진규복장미현곽진호성정훈황은아한승엽박성배김현철
Keimyung Author(s)
Jin, Kyu BokHwang, Eun AhHan, Seung YeupPark, Sung BaeKim, Hyun Chul
Department
Dept. of Internal Medicine (내과학)
Kidney Institute (신장연구소)
Journal Title
Keimyung Medical Journal
Issued Date
2006
Volume
25
Issue
1
Keyword
MalignancyMortalityRenal transplantation
Abstract
The incidence of malignancy after renal transplantation is remarkably higher than that in the general population. Therefore, malignancy represents a leading cause of morbidity and mortality in patients with a long-term surviving graft. We reviewed retrospectively the records of
676 patients who received renal transplantation between November 1982 and December 2005 and had been followed for at least 6 months post-transplantation. The overall prevalence of malignancy was 3.0%: five gastrointestinal, four lymphoproliferative diseases, four respiratory tract, two skin cancer, two native renal cell carcinoma, two thyroid, one breast. The mean age at transplantation in the malignancy cases was significantly higher than the other recipients (43.2 ± 10.5 yr vs. 35.4 ± 11.3 yr, p<0.01). The period between transplantation and the diagnosis of
malignancy was 63 ± 36.2 mo (4-161 mo). Twelve patients died with a functioning graft at an
average of 9 mo after diagnosis. In this study, malignancy was third most common cause of death
in renal transplant recipients following infection and vascular accidents. More concern should be
addressed not only to survival of the graft but also to the optimal monitoring of immunosuppression and routine regular examination to diminish the risk of malignancy.
Alternative Title
Malignancies after Renal Transplantation
Keimyung Author(s)(Kor)
진규복
황은아
한승엽
박성배
김현철
Publisher
Keimyung University School of Medicine
Citation
진규복 et al. (2006). 신이식 후 발생한 악성종양. Keimyung Medical Journal, 25(1), 1–9.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15359
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2006
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
3. Research Institutues (연구소) > Kidney Institute (신장연구소)
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