심방세동 환자에서 폐기능장애와의 상관관계

Abstract

Chronic obstructive pulmonary disease (COPD) has been associated with a high frequency of various cardiac arrhythmias, and it is not uncommon to find atrial fibrillation (AF) in COPD patients in practice. The purpose of this study was to investigate the role of reduced lung function in the prevalence of AF on a base of clinical field. We studied 128 human who presented exertional dyspnea, except the patients showing low ejection fraction (<40%), valvular heart disease and ischemic heart disease. They were divided into 65 atrial fibrillation (AF) group and 63 sinus rhythm (control) group. FEV1, FEV1% pred. and FEV1/FVC were significantly lower in AF group. In echocardiography, left atrial enlargement and hepatic vein congestion were more frequently observed in AF group, and right ventricular systolic pressure showed higher in AF group comparing to the control. It is concluded that the reduced values of FEV1, FEV1% and FEV1/FVC are associated with the prevalence of AF, and further the reduced pulmonary function might be one of the risk factors in terms of AF. Even though there were no left ventricular hypertrophy and no remarkable deterioration of ejection fraction (≥40%), we have observed the hemodynamically significant congestion and atrial enlargement in AF group with the increase of right ventricular systolic pressure.