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신증후성 출혈열 후 발생한 뇌하수체 기능저하증 1례

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Author(s)
김혜순이호영하유진박근규김남경김미경이형김상진
Keimyung Author(s)
Kim, Hye SoonPark, Keun GyuKim, Mi KyungLee, HyungKim, Sang Jin
Department
Dept. of Internal Medicine (내과학)
Dept. of Neurology (신경과학)
Journal Title
Keimyung Medical Journal
Issued Date
2010
Volume
29
Issue
1
Keyword
Empty sellaHemorrhagic fever with renal syndromeHypopituitarism
Abstract
Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a systemic infection with fever, hypotension, hemorrhage and acute renal failure. Pituitary hemorrhage and necrosis are causes of hypopituitarism often remaining undetected due to subtle clinical symptoms. We report on a patient who developed hypopituitarism as a late complication of HFRS 40 years later. His representative symptoms and signs were weakness, slurred speech, apathy, decreased muscular strength and decreased thyroid function test, which revealed low free T4 with normal
thyroid stimulating hormone consistent with secondary hypothyroidism. Combined pituitary
stimulation tests confirmed hypopituitarism and magnetic resonance imaging of the pituitary
revealed atrophic pituitary gland with an empty sella. This report suggests that patients who have
recovered from HFRS is at risk of developing hypopituitarism and should be diagnosed and treated
appropriately if suspected because unrecognized hypopituitarism significantly affects patient’s
quality of life.
Alternative Title
A Case of Hypopituitarism in Patients Who Recovered from Hemorrhagic Fever with Renal Syndrome
Keimyung Author(s)(Kor)
김혜순
박근규
김미경
이형
김상진
Publisher
Keimyung University School of Medicine
Citation
김혜순 et al. (2010). 신증후성 출혈열 후 발생한 뇌하수체 기능저하증 1례. Keimyung Medical Journal, 29(1), 63–67.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15495
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2010
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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