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1기 유방암에서 젊은 연령이 예후에 끼치는 영향

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Affiliated Author(s)
강선희
Alternative Author(s)
Kang, Sun Hee
Journal Title
Keimyung Medical Journal
Issued Date
2010
Keyword
Breast cancerPrognosisStage IYoung age.
Abstract
Purpose: The aim of this study is to assess the impact of young age on outcome in stage I breast
cancer. Method and Materials: Between 1995 and 2005, 315 patients with stage I breast cancer were
included and we reviewed medical records retrospectively. The patients were divided into three
groups, based on age at the time of diagnosis: age ≤ 35 years, 36-45 years, > 46 years. The analyzed factors were tumor size, estrogen receptor status, operation method, adjuvant treatment. Results: Of all 315 patients, 36 (11.4%) were aged ≤ 35 years, 90 (28.6%) were aged 36 to 45 years, 189 (60.0%) were aged > 45 years. The median follow up was 62.6 months (range 1.2 - 157.2) and 26 (8.25%) patients were recurred. The 5 year-disease free survival rate was 82.4% for age ≤ 35 years compared with 92.3% for age > 45 years (p=0.002). The 10 years disease
free survival showed 67.9% for age ≤ 35 years, 89.4% for age > 45 years (p=0.002). Multivariate analysis of disease free survival showed that relative risk of aged ≤ 35 years group was 2.77 times higher than aged >45 years group. For clinicopathologic factors according to age groups, aged ≤ 35 years group was more likely to have estrogen receptor negative tumors and receive adjuvant chemotherapy and breast conservation operation. Conclusions: Although prognosis of stage I breast cancer is very excellent, younger patients (age≤35) have worse prognosis than older patients. Age under 35 years is independent factor of recurrence in stage I breast cancer.
Alternative Title
Young Age as a Prognostic Factor in Stage 1 Breast Cancer
Department
Dept. of Surgery (외과학)
Publisher
Keimyung University School of Medicine
Citation
강선희. (2010). 1기 유방암에서 젊은 연령이 예후에 끼치는 영향. Keimyung Medical Journal, 29(2), 83–89.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15499
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2010
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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