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저혈압 유도성 경막외 마취와 Tranexamic Acid 투여가 주술기 출혈량에 미치는 효과

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Author(s)
이용철박지훈
Keimyung Author(s)
Lee, Yong CheolPark, Ji Hoon
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
Keimyung Medical Journal
Issued Date
2012
Volume
31
Issue
1
Keyword
Blood lossHypotensive epidural anesthesiaTotal hip replacementTranexamic acid
Abstract
We conducted present study to evaluate and compare the effect of hypotensive epidural anesthesia (HEA), tranexamic acid (TA) and combined HEA with TA on reducing perioperative blood loss and transfusion requirements in total hip replacement (THR) under general anesthesia. We reviewed medical records of primary unilateral cementless THR under general anesthesia. Twenty four patients who were underwent HEA were assigned as group 1, twenty three patients
who received TA were assigned as group 2, twenty two patients who were underwent HEA and received TA were assigned as group 3. Intraoperative blood loss in group 1, 2, and 3 was 253.5 ± 148.9, 422.4 ± 217.5, and 235.9 ± 119.4 ml, respectively. Group 2 displayed a significantly larger amount of intraoperative blood loss compared to group 1 and 3. Postoperative blood loss in group 1, 2, and 3 was 1074.5 ± 325.5, 477.0 ± 352.7, and 438.7 ± 211.3 ml, respectively. Postoperative blood loss was significantly reduced in group 2 and 3 compared with group 1. Total blood loss in group 1, 2, and 3 was 1326.4 ± 414.2, 913.9 ± 427.5, 675.2 ± 251.4 mL, respectively. Total blood loss was significantly reduced in group 2 and 3 compared with group 1. Combination of HEA and TA administration reduced both intraoperative and postoperative blood loss.
Alternative Title
Effect of Hypotensive Epidural Anesthesia and Tranexamic Acid on Perioperative Blood Loss
Keimyung Author(s)(Kor)
이용철
박지훈
Publisher
Keimyung University School of Medicine
Citation
이용철 and 박지훈. (2012). 저혈압 유도성 경막외 마취와 Tranexamic Acid 투여가 주술기 출혈량에 미치는 효과. Keimyung Medical Journal, 31(1), 56–62.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15554
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2012
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
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