과체중 및 비만한 성인 남성에서 체중력과 비알코올성 지방간과의 관련성

Abstract

Obesity is a major risk factor of non-alcoholic fatty liver diseases. Weight control is associated with the improvement of fatty liver in obese patients. However, whether history of weight change affects the occurrence of fatty liver has not been evaluated in obese patients. The purpose of this study was to investigate the relationship between individual weight change history and the presence of fatty liver in adult male patients with elevated body mass index (BMI). Survey was performed to compare the early 20s’ BMI, the highest BMI of life (HBL) and the recent BMI from 107 cases that have been found with fatty liver by ultrasonography, as well as 107 controls with similar BMI, but without fatty liver. The difference between early 20s’ BMI and recent BMI was greater in non-alcoholic fatty liver group than control group. The difference between HBL and recent BMI was less in non-alcoholic fatty liver group than control group. There was significant association between the difference of recent BMI from early 20s’ BMI and prevalence of nonalcoholic fatty liver. Hence, it may be expected that prevention of weight gain is critical to prevent non-alcoholic fatty liver even in obese patients.