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Difference of auditory brainstem responses by stimulating to round and oval window in animal experiments

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Author(s)
Jyung Hyun LeeHyo Soon ParkQun WeiMyoung Nam KimJin-Ho Cho
Keimyung Author(s)
Qun, Wei
Department
Dept. of Biomedical Engineering (의용공학과)
Journal Title
Bioengineered
Issued Date
2017
Volume
8
Issue
1
Keyword
animal experimentauditory brainstem responseimplantable hearing aidsoval window stimulationround window stimulation
Abstract
To ensure the safety and efficacy of implantable hearing aids, animal experiments are an essential developmental procedure, in particular, auditory brainstem responses (ABRs) can be used to verify the objective effectiveness of implantable hearing aids. This study measured and compared the ABRs generated when applying the same vibration stimuli to an oval window and round window. The ABRs were measured using a TDT system 3 (TDT, USA), while the vibration stimuli were applied to a round window and oval window in 4 guinea pigs using a piezo-electric transducer with a proper contact tip. A paired t-test was used to determine any differences between the ABR amplitudes when applying the stimulation to an oval window and round window. The paired t-test revealed a significant difference between the ABR amplitudes generated by the round and oval window stimulation (t = 10.079, α < .0001). Therefore, the results confirmed that the biological response to round window stimulation was not the same as that to oval window stimulation.
Keimyung Author(s)(Kor)
웨이췬
Publisher
School of Medicine
Citation
Jyung Hyun Lee et al. (2017). Difference of auditory brainstem responses by stimulating to round and oval window in animal experiments. Bioengineered, 8(1), 8–13. doi: 10.1080/21655979.2016.1226662
Type
Article
ISSN
2165-5979
DOI
10.1080/21655979.2016.1226662
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32364
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Biomedical Engineering (의용공학과)
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