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Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography

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Author(s)
Hye-Geum KimEun-Jung KongEun-Jin CheonHae-Won KimBon-Hoon Koo
Keimyung Author(s)
Kim, Hae Won
Department
Dept. of Nuclear Medicine (핵의학)
Journal Title
Clinical Psychopharmacology and Neuroscience
Issued Date
2016
Volume
14
Issue
4
Keyword
Amyloid positron emission tomographyGeriatric depressionAlzheimer diseaseSubjective memory complaint
Abstract
The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory.
Keimyung Author(s)(Kor)
김해원
Publisher
School of Medicine
Citation
Hye-Geum Kim et al. (2016). Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography. Clinical Psychopharmacology and Neuroscience, 14(4), 378–382. doi: 10.9758/cpn.2016.14.4.378
Type
Article
ISSN
1738-1088
DOI
10.9758/cpn.2016.14.4.378
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32390
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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